MICCEL – CMC

Microcrystalline Cellulose & Carboxymethyl Cellulose Sodium IP/USP

Solution for Suspensions, Lotions and Creams

  1. Suspension: As suspending agent for readily constitutable suspension Absence of sedimentation in some of formulation.
  2. Lotion: As oil/water emulsifier for lotions and creams
  3. Creams: Emulsion Stabilizer and thickener with opacifier for creams and gels.

MICCEL CMC is the mixture of microcrystalline cellulose and carboxymethyl cellulose Sodium various ratio depend on application. We produce following types of grades

Specification

Sr. no. Test Specification
1 Description Tasteless, odoriess, white, coarse to fine powder.
Solubility Swells in water, producing, when dispersed, a white, opaque dis or gel Insoluble in organic solvents and in dilute acids.
2 Identification
Test-A A white opaque, dispersion is produced that does not settle on Standing.
Test-B Each drop forms a white, opaque globule that does not disperse standing
Test-C No blue or purplish blue color produced.
3 Assay, % CMC sodium Refer chart
4 Impunities
4.1 Residue on ignition% NMT 5.0
4.2 Heavy Metals, pg/g NMT 10
5 Specific Test
5.1 Viscosity-Rotational Method, % of that stated on the label, In Cps 60.0-140.0
5.2 pH 6.0-8.0
5.3 Loss on drying, % NMT 8.0

 

Grade Wise In House Specification

Test MiCCEL CMC – 501 MICCEL CMC – 581 MICCEL CMC – 591 MICCEL CMC
Viscosity ,cps(by Labman Viscometer, Model – LMDV 200L, Spindle no. 2) Between 70 and 170
(2,1% Solid)
Between 70 and 170
(2,1% Solid)
Between 40 and 95
(1.2% Solid)
Between 50 and120
(2.6% Solid)
Assay, % (NLT 75% and NMT 125% of the labeled amount of Carboxymethylcellulose Sodium, Calculated on dried basis) 7.1 to 11.9 8.3 to 13.8 8.3 to 13.8 11.3 to 18.8
Retention on 60 # (%) NMT 0.1 NMT 0.1 NMT 0.1 NMT 0.1
Retention on 200 # (%) NMT 40  NMT 35    
Retention on 325 # (%)     NMT 45 NMT 50