Silicified Microcrystalline Cellulose – USP
Solution for Optimum Compatibility
Silicification of MCC increased physical properties such as true density, Hausner ratio, porosity, ejection force and specific surface area. Other properties such as bulk and tap densities were reduced due to the amorphous and light character of fumed silica.
MICCEL S is the mixture of microcrystalline cellulose and colloidal silicon dioxide (MCC/CSD at 98:2 ratio) and most compactible grade of SMC with flow characteristics similar to doubling the parties size of MCC.
|White or almost white, very fine to moderately fine powder. It is a free-flowing material.
Slightly soluble in sodium hydroxide solution (1 in 20); practically insoluble in water, in acetone, in ethanol, in toluene, and in diluted acid.
Test-A (IR Absorption)
Test-D(silica dispersion uniformity test)
Should be comply
The substance takes on a violet-blue color should be produced.
A deep yellow color is produced
|3.1||Heavy Metals, µg/g||NMT 10|
|4.1||Residue on Ignition, %||1.8 – 2.2|
Total Aerobic Microbial Count, CFU/g
Loss on Drying, %
Degree of Polymerization
Particle Size Distribution
Water Soluble Substances, %
Ether Soluble Substances, %
5.0 – 7.5
Grade Wise In House Specification
|Test||MICCEL S-101||MICCEL S-102||MICCEL S-112|
|Loss on drying (%)||NMT 7.0||NMT 7.0||NMT 1.5|
|Bulk Density, g/ml||0.28 to 0.33||0.25 to 0.37||0.25 to 0.37|
|% Retention on 60 #||NMT 1||NMT 8||NMT 8|
|% Retention on 200#||NMT 30||NLT 45||NLT 45|