Microcrystalline Cellulose Powder IP/BP/EP/USP/NF/JP

Microcrystalline Cellulose IP/BP/USP/JP/EP

USFDA TYPE IV DMF NO. 026433

Microcrystalline Cellulose IP/BP/USP/JP/EP

The MICCEL grades of Microcrystalline Cellulose of Ankit Pulps and Boards, are widely accepted excipients by a number of leading pharmaceutical industries in India for its quality, consistency and customer service. Microcrystalline Cellulose revolutionized tableting because of its unique compressibility and carrying capacity. Its exhibits excellent properties as an excipient for solid dosages forms, compact well under minimum compression pressures, has high binding capability and creates tablets that are extremely hard & stable, yet disintegrate rapidly.

Product

MICCEL 101 Wet granulation and direct compressible
MICCEL 102 Direct compressible & large particle size
MICCEL 103, MICCEL 112, MICCEL 113 Ideal for moisture sensitive material
MICCEL 114 Directly compressible
MICCEL 105 Enhanced compressibility with combination
MICCEL 200, MICCEL 500, MICCEL 1000 Increase flow ability & Direct compressible
MICCEL 301 Higher Density, Greater tablet wt.
MICCEL 302 Direct compressible, Greater tablet wt.
MICCEL12 Direct compressible
MICCEL W, MICCEL WP Wet granulation
MICCEL-102 BD Higher density & increase flow

Tablets Manufacturing – Applications

Process Advantages Methods of use
A. Direct Compression Chemical purity, binder, disintegrant, flow aid, filler, inertness Table making by direct compression involves only weighing mixing & compressing
B. Wet Granulation Binder, rapid wicking action, permits fast additional of granulation fluid being most absorbent, most inert

Miccel Features

-> Excellent hardness levels at low compression forces

-> Low Lubricant sensitivity

-> Low Tablet Friability

-> Good Disintegration aid

-> Super Stability

Performing in Tablets & Capsules Making

Chemical Purity Non-reactive Organic ingredient, Extremely Low level of organic & Inorganic
Binder High Hardness level, low friability
Disintegrant Keep Uniform Concentration of drug in solution
Flow aid Require less Lubricant than other typical binders.
Inertness Drug chemical status is maintained.
Absorbent Keeps drugs uniformly mixed.

Quantum to be used

The amount to be used in direct compression characteristic of the formulation’s other ingredients.

-> Typical use level is of 15 to 20%

-> Granulation use level 15%

-> Levels in excess of 90% has been reported

Co-Processed MCC

Co-processing could lead to formation of excipients with superior quality product compare to the simple physical mixture of their components. Co-processing results in a product with added value related to the ratio of its functionality and price. Development of co-processed directly compressible adjuvant, starts with the selected of the excipients to be combined, their preparation method to get an optimized product with desired physic-chemical parameters.

* We can make custmize excipients according to your requirement.

Grade in house Specification

Test MICCEL 101 MICCEL 102 MICCEL 103 MICCEL 112 MICCEL 113 MICCEL 114
LOD , % * NMT 7.0/NMT 6.0 * NMT 7.0/NMT 6.0 NMT 2.0 NMT 1.5 NMT 1.5 * NMT 7.0/NMT 6.0
BD, g/ml 0.22 to 0.34 0.22 to 0.34 0.26 to 0.31 0.28 to 0.38 0.27 to 0.34 0.34 to 0.43
+ 60 #, % NMT 1 NMT 8 NMT 1 NMT 8 NMT 1 NMT 8
+ 200 #, % NMT 30 NLT 45 NMT 30 NLT 45 NMT 30 NLT 40 and NMT 60
Test MICCEL 1000 MICCEL 301 MICCEL 302 MICCEL 102 BD MICCEL W MICCEL WP
LOD , % * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0
BD, g/ml 0.10 to 0.15 0.34 to 0.51 0.35 to 0.50 0.30 to 0.40 0.25 to 0.35 0.24 to 0.35
+ 60 #, % NMT 0.5 NMT 1 NMT 8 NMT 8 NMT 1 NMT 8
+ 200 #, % NMT 20 NMT30 NLT 45 NLT 50 NMT 35 NMT 35
Test MICCEL 1000 MICCEL 301 MICCEL 302 MICCEL 102 BD MICCEL W MICCEL WP
LOD , % * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0 * NMT 7.0/ NMT 6.0
BD, g/ml 0.10 to 0.15 0.34 to 0.51 0.35 to 0.50 0.30 to 0.40 0.25 to 0.35 0.24 to 0.35
+ 60 #, % NMT 0.5 NMT 1 NMT 8 NMT 8 NMT 1 NMT 8
+ 200 #, % NMT 20 NMT30 NLT 45 NLT 50 NMT 35 NMT 35
Test MICCEL 12 Test MICCEL 200 Test MICCEL 105 MICCEL 500
LOD , % * NMT 7.0/NMT 6.0 LOD , % * NMT 7.0/NMT 6.0 LOD , % * NMT 7.0/NMT 6.0 * NMT 7.0/NMT 6.0
BD, g/ml 0.25 to 0.37 BD, g/ml 0.29 to 0.36 BD, g/ml 0.20 to 0.30 0.27 to 0.37
+ 40 #, % NMT 1 + 60 #, % NLT 10 + 60 #, % NLT 50
+100 #, % NMT 50 + 100 #, % NLT 50 + 400 #, % NMT 1
+325 #, % NLT 70

LOD : Loss on drying, BD: Bulk density

Note : (*) Loss on drying as per IP NMT 6.0 % and as per BP/EP/USP/JP NMT 7.0 %.

-> Low Moisture Grade: MICCEL 112, MICCEL 113, MICCEL 103.

-> High Bulk Density Grade: MICCEL 301, MICCEL 302, MICCEL 102 BD.

-> Directly Compressible Grade: MICCEL 102, MICCEL 102 BD, MICCEL 112, MICCEL 114, MICCEL 200, MICCEL 302.

-> Wet Granulation: MICCEL 101, MICCEL 105, MICCEL 301, MICCEL W, MICCEL WP.

-> Superior Flow: MICCEL 200, MICCEL 500.

-> Super Compatibility: MICCEL 105.

Packaging Details

Available Packaging Type

Type Size
HDPE Bags 25Kg
Fibreboard Drum 25Kg

*Our standard packaging in 25 Kg bags. We can also customize packaging as per customers request at additional cost

Container Palletized Non-Palletized
20 Ft. (Approx Wt.) 10,000 Kg 11,000 Kg
40 Ft. (Approx Wt.) 20,000 Kg 25,000 Kg

Unique Features of Microcrystalline Cellulose

Angle of Repose

Customized Bulk Density

Excellent Flowability

Better Compressibility

Enquire Now
close slider