USFDA TYPE IV DMF NO. 031300
Silicified Microcrystalline Cellulose – USP
Solution for Optimum Compatibility
Silicification of MCC increased physical properties such as true density, Hausner ratio, porosity, ejection force and specific surface area. Other properties such as bulk and tap densities were reduced due to the amorphous and light character of fumed silica.
MICCEL S is the mixture of microcrystalline cellulose and colloidal silicon dioxide (MCC/CSD at 98:2 ratio) and most compactible grade of SMC with flow characteristics similar to doubling the parties size of MCC.
Specification
| Sr.no. | Test | Specification |
|---|---|---|
| 1. | Description | White or almost white, very fine to moderately fine powder. It is a free-flowing material. |
| Solubility | Slightly soluble in sodium hydroxide solution (1 in 20); practically insoluble in water, in acetone, in ethanol, in toluene, and in diluted acid. | |
| 2. | Identification | |
| Test-A (IR Absorption) | Should be comply | |
| Test-B | The substance takes on a violet-blue color should be produced. | |
| Test-C | A deep yellow color is produced | |
| Test-D(silica dispersion uniformity test) | NMT 0.02 | |
| 3. | Impurities | |
| Heavy Metals, µg/g | NMT 10 | |
| 4. | Specific Tests | |
| Residue on Ignition, % | 1.8 – 2.2 | |
| 5. | Microbiological Analysis | |
| Total Aerobic Microbial Count, CFU/g | NMT 1000 | |
| Total Combined Molds and Yeasts Count, CFU/g | NMT100 | |
| Escherichia Coli/g | Should be absent | |
| Pseudomonas Aeruginosa/g | Should be absent | |
| Staphylococcus Aureus/ g | Should be absent | |
| Salmonella Species/ 10g | Should be absent | |
| 6. | Conductivity, µS/cm | NMT 75 |
| pH | 5.0 – 7.5 | |
| Loss on Drying, % | NMT 7.0 | |
| Degree of Polymerization | NMT 350 | |
| Bulk Density | Refer chart | |
| Particle Size Distribution | Refer chart | |
| Water Soluble Substances, % | NMT 0.25 | |
| Ether Soluble Substances, % | NMT 0.25 |
Grade Wise In House Specification
| Test | MICCEL S-101 | MICCEL S-102 | MICCEL S-102 HD | MICCEL S-112 |
|---|---|---|---|---|
| Loss on drying (%) | NMT 7.0 | NMT 7.0 | NMT 7.0 | NMT 1.5 |
| Bulk Density, g/ml | 0.28 to 0.33 | 0.25 to 0.37 | 0.38 to 0.50 | 0.25 to 0.37 |
| % Retention on 60 # | NMT 1 | NMT 8 | NMT 8 | NMT 8 |
| % Retention on 200# | NMT 30 | NLT 45 | NLT 45 | NLT 45 |
Packaging Details
Available Packaging Type
| Type | Size |
|---|---|
| HDPE Bags | 25Kg |
| Fibreboard Drum | 25Kg |
*Our standard packaging in 25 Kg bags. We can also customize packaging as per customers request at additional cost
| Container | Palletized | Non-Palletized |
|---|---|---|
| 20 Ft. (Approx Wt.) | 10,000 Kg | 11,000 Kg |
| 40 Ft. (Approx Wt.) | 20,000 Kg | 25,000 Kg |
Unique Features of Microcrystalline Cellulose
Angle of Repose
Customized Bulk Density
Excellent Flowability
Better Compressibility
