Solution for Optimum Compatibility
Silicification of MCC increased physical properties such as true density, Hausner ratio, porosity, ejection force and specific surface area. Other properties such as bulk and tap densities were reduced due to the amorphous and light character of fumed silica.
MICCEL S is the mixture of microcrystalline cellulose and colloidal silicon dioxide (MCC/CSD at 98:2 ratio) and most compactible grade of SMC with flow characteristics similar to doubling the parties size of MCC.
| Sr.no. | Test | Specification |
| 1. | Description | White or almost white, very fine to moderately fine powder. It is a free-flowing material. |
| Solubility | Slightly soluble in sodium hydroxide solution (1 in 20); practically insoluble in water, in acetone, in ethanol, in toluene, and in diluted acid. | |
| 2. | Identification | |
| Test-A (IR Absorption) | Should be comply | |
| Test-B | The substance takes on a violet-blue color should be produced. | |
| Test-C | A deep yellow color is produced | |
| Test-D(silica dispersion uniformity test) | NMT 0.02 | |
| 3. | Impurities | |
| Heavy Metals, µg/g | NMT 10 | |
| 4. | Specific Tests | |
| Residue on Ignition, % | 1.8 – 2.2 | |
| 5 | Microbiological Analysis | |
| Total Aerobic Microbial Count, CFU/g | NMT 1000 | |
| Total Combined Molds and Yeasts Count, CFU/g | NMT100 | |
| Escherichia Coli/g | Should be absent | |
| Pseudomonas Aeruginosa/g | Should be absent | |
| Staphylococcus Aureus/ g | Should be absent | |
| Salmonella Species/ 10g | Should be absent | |
| 6. | Conductivity, µS/cm | NMT 75 |
| pH | 5.0 – 7.5 | |
| Loss on Drying, % | NMT 7.0 | |
| Degree of Polymerization | NMT 350 | |
| Bulk Density | Refer chart | |
| Particle Size Distribution | Refer chart | |
| Water Soluble Substances, % | NMT 0.25 | |
| Ether Soluble Substances, % | NMT 0.25 |
Grade Wise In House Specification
| Test | MICCEL S-101 | MICCEL S-102 | MICCEL S-102 HD | MICCEL S-112 |
| Loss on drying (%) | NMT 7.0 | NMT 7.0 | NMT 7.0 | NMT 1.5 |
| Bulk Density, g/ml | 0.28 to 0.33 | 0.25 to 0.37 | 0.38 to 0.50 | 0.25 to 0.37 |
| % Retention on 60 # | NMT 1 | NMT 8 | NMT 8 | NMT 8 |
| % Retention on 200# | NMT 30 | NLT 45 | NLT 45 | NLT 45 |
Packaging Details
Packaging Details
| Type | Size |
| HDPE/Paper bags | 25Kg |
| Fiberboard/HDPE | 25Kg |
*Our standard packaging in 25 Kg bags. We can also customize packaging as per customers request at additional cost
| Container | Palletized | Non-Palletized |
| 20 Ft. (Approx Wt.) | 10,000 Kg | 11,000 Kg |
| 40 Ft. (Approx Wt.) | 20,000 Kg | 25,000 Kg |
Unique Features of Silicified Microcrystalline Cellulose – USP
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- Angle of Repose
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- Customized Bulk Density
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- Excellent Flowability
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- Better Compressibility
Frequently Asked Questions
Silicified microcrystalline cellulose is a mixture of microcrystalline cellulose (MCC) and colloidal SiO2 in a 98:2 ratio. It is utilized in the pharmaceutical industry to enhance flowability and ensure uniformity in various formulations.
Ankit Pulps and Boards’ silicified microcrystalline cellulose stands out due to the meticulous care taken in its production technology. We use premium quality raw materials to achieve optimum physical properties, including density, Hausner ratio, porosity, and ejection force.
Please share enquiry/sample request on sales@celluloseankit.com
Yes, our pharmaceutical excipients are 100% compliant with regulatory standards, including USP and EP. We have an FDA-approved in-house R&D Lab.
Bulk quantity order enquiries of 1 MT or above can be placed on sales@celluloseankit.com
Yes, our proficient technical team is capable of meeting your customization needs.
Retest date of silicified microcrystalline cellulose is 3 years from the date of manufacturing. It should be stroed in a closed ambient environment.